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This patient came to the OPD with chief complaint of intense pruritus. What is your clinical impression?


Case Courtesy :

Dr. Sravani Bikkina

PG in Dermatology

KIMS, HYD

Tags: karuturi.rounds

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larve migrans...

cutaneous larva migrans

cutaneous larvae migrans

cutaneous larva migrans

cutaneous larva migrans

cutaneous larva migrans

Cutaneous larva migrans.

Cutaneous Larvae Migrans

Its Cutaneous Larva Migrans or Creeping eruption or Plumber’s itch or Creeping verminous dermatitis or Sand worm eruption or Duck hunter’s itch.




CUTANEOUS LARVA MIGRANS

Definition and Etiology

Cutaneous larva migrans (CLM) is an infestation by a nematode, most often the animal hookworm(Ancylostoma caninum or Ancylostoma braziliense), less often the human hookworm (Ancylostoma duodenale and Necator americanus).

CLM occurs most commonly in areas with warm climates such as Africa, Asia, Latin America, and the southeastern United States. It is the most common travel-related skin disease, often occurring in travelers who have visited these areas.

Pathophysiology and Natural History

CLM is a self-limited disease, invariably acquired when the skin has contact with sand or soil contaminated with animal feces. The feet are the most common affected site, and the legs and buttocks are less so. Left untreated, the disease resolves within a few months.

Signs, Symptoms, and Diagnosis

Affected patients have itchy erythematous, serpiginous tracks, usually on the feet, buttocks, or thighs. The track advances 1 to 2 cm/day.

The history and pattern of skin disease (serpiginous tracks) and its location should suggest the diagnosis.

CLM must be clinically differentiated from migratory myiasis and cutaneous larva currens. Migratory myiasis extends more slowly; the fly larvae are usually larger and survive longer. Cutaneous larva currens is the infestation with the roundworm Strongyloides stercoralis. The sign is pruritic, serpiginous, erythematous tracks on the perineal area, buttocks, and thighs, which evolve rapidly at a rate of 5 to 15 cm/hr. This differentiation is important, because cutaneous larva currens may be associated with systemic or disseminated infection with a mortality rate of up to 70% to 90%

Treatment

Several treatment strategies exist. The most common treatments are thiabendazole cream 2 or 3 times a day for 5 to 10 days, albendazole 400 mg orally daily for 3 to 5 days, and ivermectin as a single dose of 12 mg (200 mcg/kg).

Reference : Cleveland Clinic: Current Clinical Medicine, 2nd ed.

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